Redefining How We Choose Skincare: Powered by Advanced Stem Cell Science
Many of our clients come to us feeling confused or let down by skincare that promised a lot-
and delivered very little.
That’s why, we at Medifine choose a different approach.
Rather than offering an endless selection of products, we deliberately keep our ranges
considered and purposeful. Each brand we stock earns its place through evidence, integrity
and results that prioritise skin health over hype.
Our philosophy has never been about having the most products its about having the right
ones.
- We prioritise skin function over surface correction
- We value barrier integrity, inflammation control and long-term resilience
- We favour brands rooted in science, regenerative support and ethical formulation
Introducing One of the Brands We’ve Chosen to Work With
- As part of our commitment to sourcing exceptional skincare, we’ve chosen to
introduce our brands slowly and thoughtfully – one at a time. - Each brand we stock has earned its place through careful evaluation, clinical
experience, and results we trust. Rather than overwhelming you with options, we
want to take the time to explain why each brand matters, how it supports skin
health, and who it is best suited for. - The first brand we’d like to introduce is Neogenesis – a brand that aligns closely
with our philosophy of intelligent, evidence-led skincare.
Neogenesis is a range that targets skin regeneration at a cellular communication level,
not just hydration, exfoliation, or pigment suppression. It is one of the very few skincare lines
that directly supports repair, healing, inflammation control, and postprocedure recovery
without irritating compromised skin.
Neogenesis helps your skin heal and function better at a cellular level. It doesn’t force change
through irritation – it supports your skin’s natural repair mechanisms, which is why we use it
when skin is fragile, inflamed, or posttreatment.
What makes Neogenesis unique?
1. Humanderived growth factor technology (nonliving)
Neogenesis uses bioidentical human growth factors and cytokines, not plant substitutes
and not synthetic peptides.
- These are signalling molecules that:
o Stimulate fibroblast activity
o Improve collagen and elastin synthesis
o Accelerate wound healing
o Improve barrier repair
2. Works when other actives can’t
Neogenesis is especially valuable when:
- Skin is inflamed, sensitised, or barrierimpaired
- Postlaser, needling, RF, or peel recovery
- Rosaceaprone, perioral dermatitis, eczemaprone skin
- Menopausal, immune compromised, or slow healing skin
Unlike retinoids or acids, Neogenesis can be used during recovery phases instead of being
stopped.
3. True regenerative support, not just “antiageing”
Most skincare:
- Exfoliates
- Stimulates irritation based turnover
- Suppresses pigment
- Temporarily plumps
Neogenesis:
- Improves the skin’s ability to function and repair itself
- Supports longterm skin resilience, not short term “glow”
- Strengthens results from in-clinic treatments
This is especially important in:
- Thin, postmenopausal skin
- Chronically inflamed skin
- Over treated skin
4. Anti-inflammatory rather than pro-inflammatory
Many “active” skincare ranges rely on controlled inflammation.
Neogenesis instead:
- Reduces inflammatory cytokines
- Improves healing without triggering flareups
- Lowers the risk of post-inflammatory hyperpigmentation (PIH)
✔️ This is why it’s so useful in Fitzpatrick IV–VI, rosacea, and pigment prone patients.
5. Clinically versatile across treatment plans
Neogenesis fits into:
- Pretreatment skin conditioning
- Post-procedure recovery
- Pigment protocols (alongside cysteamine, tranexamic acid, LED)
- Barrier repair programmes
- Longterm skin health maintenance
It doesn’t “fight” other actives – it supports their results and reduces complications.
6. Minimal formulas, maximal outcome
- Fragrance free
- No unnecessary fillers
- Low irritation risk
- Highly concentrated activesThis makes it ideal for:
- Sensitive patients
- Medicalled aesthetic clinics
- Clients who have failed multiple skincare lines
Clarification:
Human-derived growth factors” and “stem cell conditioned media” are referring to the
same biological source, just described at different levels of detail.
- Product labels use the scientific manufacturing term which is human stem cell
conditioned media - In this blog we have referred to human derived growth factor technology- both are
correct
What “stem cell conditioned media” means
In a laboratory, adult human skin stem cells are grown. As they grow, they release:
o Growth factors
o Cytokines
o Peptides
o Signalling proteins
- These molecules collect in the surrounding solution
- That solution is called stem cell conditioned media
- The cells are then removed
✅ What’s left is humanderived growth factors and signalling molecules
❌ There are no stem cells or genetic material in the final product
Summary:
Neogenesis products contain NeoGenesis S²RM® technology (Stem Cell-Released
Molecules).
S²RM® = Stem Cell Released Molecules (from two or more stem cell types).
It is a patented, cellfree regenerative technology developed by NeoGenesis and based on
adult human stem cell science.
Instead of putting live stem cells on the skin (which is not allowed or effective in cosmetics),
NeoGenesis uses the bioactive molecules that stem cells naturally release to repair tissue
without irritation.
S²RM® Molecules are packaged in exosomes
The released molecules are naturally enclosed in exosomes—nanosized lipid vesicles that:
- Protect the molecules
- Improve penetration
- Deliver signals directly to skin cells
Exosomes are the key delivery system in S²RM®, making it more effective than growth factors
alone.
Safety and oncology relevance
It is considered oncology-safe and is one of the most recommended medical-grade skincare lines
for patients undergoing or recovering from cancer treatment.
Our Recommendations: Hero Products
S²RM® concentrations in NeoGenesis products (important clinically)
NeoGenesis products differ mainly by S²RM® concentration, not by “strength”
- Recovery Serum – ~70% S²RM®
For post-procedure, trauma, barrier failure, advanced aging
- Booster Serum – ~40% S²RM®
For redness, rosacea, inflammation, sensitised skin - Skin Serum – ~20% S²RM®
Daily regenerative support, hydration, acne-prone and ageing skin
- Moisturising Mist – ~1% S²RM®
Maintenance, hydration, treatment room use.
What “strength” means with S²RM®
With NeoGenesis, strength = concentration of signalling complexity, not stimulation
pressure.
When you go from:
- Skin Serum → Booster → Recovery
You are increasing:
✅ Quantity of stem-cell released molecules
✅ Breadth of signals (growth factors, cytokines, peptides)
✅ Repair information delivered
You are not increasing:
❌ Irritation
❌ Inflammation
❌ Forced cell turnover
That’s why Recovery (70% S²RM®) can be used:
- Immediately post laser
- On oncology skin
- On severely compromised barriers
If it were “strong” in an aggressive sense, this would be impossible.
We love sharing skincare brands we truly stand behind – and NeoGenesis is one of them.
Thoughtfully formulated, clinically intelligent, and trusted in our treatment room.
You can now explore and purchase our recommended skincare directly through the clinic or
purchase from
Medifine Skin Clinic/Aesthetics & Online Shop- medifine.co.uk
If you want further information,
Send an email to info@medifine.co.uk or tele: 0113 225 3938
✨ Shop our favourites and give your skin the care it deserves.