Cyspera – Intensive Pigment Corrector UK Stockist
Cyspera® is the novel pigment corrector formulated with Cysteamine to address the appearance of discoloration.


What is Hyperpigmentation? 

Hyperpigmentation is a common skin condition in which some areas of the skin become darker in colour than the surrounding skin.
Hyperpigmentation occurs when an excess of melanin is produced by melanocytes, the pigment cells, and then moved up to the skin’s surface. Hyperpigmentation can be caused by inflammation, hormonal stress, sun damage, or other skin injuries. People with darker skin tones are more prone to hyperpigmentation, especially with excess sun exposure. Addressing stubborn hyperpigmentation concerns is a long and difficult process. It is important to keep in mind that there is no quick fix. Hyperpigmentation needs time, patience, and compliance with the daily program over weeks.


Why Cyspera?

Cyspera® is the novel pigment corrector formulated with Cysteamine to address the appearance of discolouration and dark spots.

Significant pigment correction

67% pigment correction in stubborn discoloration

Superior benefit to risk ratio

Compared to all other pigment correcting agents

Highly biocompatible & well tolerated

92% user & 100% investigator satisfaction

Non-cytotoxic, non-carcinogenic

free of hydroquinone, retinoic acid, corticosteroid



Clinically Proven Results

67% pigment correction in stubborn dicoloration

90% noticed significant improvement in the appearance of discoloration


Clinical cases

Courtesy of Dr. Huang Yung-Hsueh (Taiwan)After 2 monthsAfter 3 months
The Science behind Cysteamine

In 1966, Dr. Chavin injected Cysteamine into black goldfish skin and observed significant pigment correction.

In 1968, Drs. Frenk, Pathak and Bleehen observed that cysteamine is significantly stronger than hydroquinone in vivo. Its instability prohibited its formulation as a topical product.

In 2000, Dr. Qui investigated the pigment correcting effect of cysteamine in vitro which resulted in 80% reduction of melanin in vitro.

The new technology significantly increases cysteamine stability and reduces its odor. Topical cysteamine was formulated.

In 2013, a first case series gave clues about the significant efficacy. Dr Hsu presented first cases on 30 subjects and reviewed existing research results.


How to Apply Cyspera


  • Do not wash the skin before application. If it is necessary to wash the area, wait for one hour before application.
  • Apply a thin layer on the skin. Leave on for 15 minutes (a warming sensation or mild tingling may occur and last up to 30 minutes).
  • Remove by washing the area with a gentle cleanser Pat dry.
  • Apply moisturiser


Intensive phase:

Once per day, everyday, for 16 weeks.

Maintenance phase:

Apply once per day, twice-weekly to maintain results long-term.

Optimal Results:

Daily use of a broad spectrum sunscreen  with SPF 30 or higher is highly recommended.

Do not use if you are pregnant, lactating or planning to become pregnant. Do not use if you or someone in your immediate family suffers from vitiligo.


How to Purchase 


Please contact Medifine via email on for more information or to purchase this product.

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